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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461c34733497c79d54f9b5731a932010f5416d16493abed709d550a8a0712f58' 
  AND token = '/kNg85kcVJSmw48agY+LP0ipWGUVk3gO6qmabrcIBsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}