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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e0b7d3a1fbc19c6ff59fe68a053af844396ba3ec4e42cee7607a555670a256' 
  AND token = 'OTdfvy0CKGlhG9GsO2sfsRZy/CHKy7lGICvqiOUI9Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}