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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df9afd8ed44b414769891a2cd46cd121ac148cbe42377ed904f007a647e35da' 
  AND token = 'bjX0BLW+/xNUvRRisfjeZCma9ul/AgupeNMQpkYfFUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}