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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ddb88063b0908b8087c5eb0bb41610c07e67eb988a70e300897f72be732267a' 
  AND token = 'gBmkuaCZNaK44uOKSG62NqCGgR509izlWEQ4N4DnU8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}