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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f09c65994e2d4c7588cf96464b3fa462b427e04b44340524f925815d20c1fee4' 
  AND token = 'rbhb6zaAfDa1nZ1i0+PK7UwvNLN3K8AgblsLtrzAAe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}