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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed15abea03e60ba30acdca889fbc367ff6cc0ec5793550550292d487b0db81e0' 
  AND token = 'FSewVCdd/S1uU+G7tIcemAtmxZlYeh/3icwK5a3Rcyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}