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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470744c265f0dc99f0561f10b4dc1c1b8dcada1980f25eb6a965b83ec8dc5894' 
  AND token = 'vKtb9b3sBjlqpL1I5FySge1h0CrT24xvBFyIFwC8EAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}