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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e0ed47c3e0a4b934b6e0db10036d60ad1941a8d8e69d6a769882dc1c36be65' 
  AND token = 'A75zUBSISby4lHxJBUwXVYS22t4PousqbX3w2UxpRnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}