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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5feb4941289733d2d661038ea3c53e58109d1164693c0ff83aedcca4434a76' 
  AND token = 'E2WWQGJjbqMEwY/uGFKEJ9lTkmBC1oo5/caK4ZC33eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}