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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df36f8fe7b10670225db3812b7fdc2ef194b6307aec2760320ccb21148744aa9' 
  AND token = '1c6uK/N8lc2x9wQaGTfsnZGEddwa+UUuTsuKLE4dAn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}