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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f97bd07ea0a149fe1bbbb4ce8f25e131e40c770015349edfe9a81b987244e35d' 
  AND token = 'eEOcU4qNfiuVhExRMt4djzbhvC8EIzmfM/4P6wNYzcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}