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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bf37036a6dca34b05f484814b140fa066386020732b28b6796411b7a6667bf' 
  AND token = 'bhM3TJ8F+j001WUzRX5LbPsNIz83O/eH1kLDccW8rTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}