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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7b2962dd1087ddaa7b67209048dce1854eb6cdb1bb240e46e0d87dc91bdacd' 
  AND token = 'RO4gx5QieKf8wLyE8rz08pG32i9LkhbsVFPUcay1zMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}