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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48849e52028b65a3033376751606931fa82f315dfa73f6d7069818183fd57263' 
  AND token = 'nlS0XOoSsSZYHviGo3g/INxjdDxPTMsbseo5di8jSII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}