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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4551970edf6d09850d67813cacd781d49354cdeeb3ce85477038911c798204f' 
  AND token = 'aMin5xkwXxqDzOTiKO2KxYzuNWC8P2bLQ1NoYRgDQms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}