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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df792425bc7232c5c306a878f5d6a316de65227a673a9af05ebd2d1da3ec3b7a' 
  AND token = 'GHD/9oLfkMYjK5FBrE+LWIKOAm/ozZ5Ok6vwrz7SDuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}