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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef58be226f2a75aded17e1bad20b8d4d43323ee65157d804ffb2319a4d4d32a' 
  AND token = 'LoJRQPYN5PFZD3CbnU8p5he49+um5hA2oKhYqTCW6r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}