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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c5b599d66f2e2f279051d6bc212a01d897e015ccfc83906c08d73635fba08a' 
  AND token = 'GtG+iDP/pl1hzxyftfHXP/scHltRIxm7VZpb1TrFrLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}