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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256b4814c285c62ebc0e030623044bcd1867c47e06a9b1dd5580a5e1e9abdb71' 
  AND token = '0JYb1Q+HK2rMnKQisTgv7QwWiOjUfvjYfhtkwcJdfFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}