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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ea14c09299f3479a7fcb38086bcb465f10c368e239b814180cd2d2d71dda66' 
  AND token = '/yb4x864DQfMoqwqpIKLThyXZ6cRJnALcF0UGh0X73M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}