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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356a524f58cb252c1b9071bb2a45dc1f36fee6d89a4d615c099207ba1027b07e' 
  AND token = '5fqxl1RTs8/+CKYSGxR9xeXW3qeYon4aQUMuf5xDPTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}