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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3246e22a84e3f525c58c531b3b4eba40585388cf4c8968a0d7be7616f4fe8a6' 
  AND token = 'ujxA3NY4aE9mxRxiDDvUbjFP5JB5ZNEohmc2QmUKD9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}