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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee9e7629844c385a4a96b33d85209814b11c4e21dd8771d87609cd61726352a' 
  AND token = '6NGNSsxCvamIb0SsNtAQOzMtGviD9NTTIQcVdekRss4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}