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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd859d8fae2475afd72ecffbdaf1dbb53c3d14811f3537e1eddfa9288a74a365a' 
  AND token = '9kY2iYuRDxNC8aSU4GobDKxAWbL+yn4Dk4c40M/T864=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}