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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eebf38641c031bb4c8c0a74ff22f1ef9a8d19014a09102d89c6190f5bf5350d' 
  AND token = 'H5CHeKeM2Qk5NJHYggS8jgDJVoscD9/I1oNFB8I/uXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}