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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7728fd48a0a6023eb585c6d6b22ca39faaf12386b5e6a3f4ad92d26aa03da9' 
  AND token = '/KRKULUadOTUQ4GGIX+/1Lk9TOo9EQ2nsgWjgLeeIUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}