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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5663741a25a0d9aee3001b1f6d9b2dff759bc419801bf2fc9a917323df358686' 
  AND token = '5sE3E9pw4rdgFvqB+RDq2O2/8xb2tzsd3ChT00eOd1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}