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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9819907a4aed97dbae129cb92a42f8567ea1910e1414613f5f74a370a0c1a816' 
  AND token = 'rLUBaH04udj6gqynUmNhL2i5JpYTHiqsszzwNwYGxTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}