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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4ba3a9d47e7902695facc2800b760b8f699a3e207574f07f1e3f1cdcca421f2' 
  AND token = 'zzD3jIO/BRHqbJ4cAxSD0yeVdL0j7yQD4VJukaXN3x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}