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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73edbf867e35939289dad34f0f980a93100cb6d39a5704fb315a815a4a0ff4d' 
  AND token = 'B28H9PEsqUNr/YkExeVYcjWqIeUC0umQqk84IMJChwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}