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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9694742c401fd2c95446996e46cdc23185267068f443aa3961e05b96c9d83f55' 
  AND token = 'JRkoErY/Peeb2twoiMi8C0vXVF+ag1Klm+4y+q4+9Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}