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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e530334706d623093cd3751f026b3e1c34192c402d2f7997c2e45037d62ed19' 
  AND token = 'x5IpQVVqL6AZdr7EfLWFwxxBKL5P6tMUFQYi7XFhclE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}