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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de075fb793c3874c651d1f863937a22d5ffd14d558cf7ced32e74f02502f24c3' 
  AND token = 'Wlj7/u2o3ha5DJ1wZEesWobxbBLcJZnhqxMLbPFHl04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}