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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49ad6c28da4e9fc8deb643b7cb414c962e8e90a3691c17025a34da682cc5003' 
  AND token = '7uUdXU/PLWzKeIZH1UWZXkOXBjaDXhC4ah8I2OPJMYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}