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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ad176d7500ecfea23c12a255dbd6018cc2a40bf87723e8914847fe3e1b7bbb' 
  AND token = '6W8Y6Wji9ReZjeDpdAJIzlogPYDUrs7tMV5II+vioQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}