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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b43dbe6c9d0a83b09093ba9a55f2ecfc6bf8a8381dacfaab87e276696041c14' 
  AND token = 'FVgbRFw8gaZSNAg/ICjGjQsPJVc7nveU+gps9ynrc8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}