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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b00adbb614d03a3a5111b694d73bec658837e5ef9913aae1b69be0cda2f6240' 
  AND token = 'O9DCfs/0oPriiERIV2Mwu2wC6YwI239xCsALc6M1zMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}