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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36b2966b5c13b971d0a7bef4d622ec55a9e1a14e343dd8dc9f1e51fed7c7ce8' 
  AND token = '15PuI6T7p+wC8avZ6E+1frVsbgCaiQguY/0xQvbHXbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}