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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '364f0f03359295c3bba258997f0e96c69f1f6bc8693c9ce846aee7f575485158' 
  AND token = 'V7Zf0+Ts2KP8YWYMKlh4sxfWfdfYd7KjAyP0j3CvPi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}