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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4daac6e546b3d95d11c6d197b9a25c7ebe83273a987aea5bb7666b4923e4bc07' 
  AND token = 'PMxLWdhvCDlIpxpDqie2lIMbjaYdyESpCk9EL9yg7Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}