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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b444f474004ecfba4bb9e12106a015a9baa6ed4c279c52a9a94122e7a57781a' 
  AND token = 'j9O6c2yx2tDbRLGVA1V0UHTalLUu5rc8NaRRE3uqptA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}