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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d57cdecbf2d359f76ab49e877776e4f346a1db26edcbc00a27df5d888e0fed6' 
  AND token = 'gwnxW1Epi01ElLIMWEU+xl7KHwjWIQby/3YLsjeG4Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}