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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b282f295136ca72090978e2dd885c04a940315a8d18f91cc483eb377a19d67e2' 
  AND token = 'WEenHCwCnEBIfCWpELNcA0AuBq9PytVbTA7HrkV5nQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}