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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba072246b03919164f82de8c6eb1cdbe2e4f2138dbff4819f42ede8dc62ce5d' 
  AND token = 'E12E/utDwoPax1aFNzckgQJZCREkUFpxVmcQw3SEu94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}