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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c351dbef7e42c25b3fa078b88c8eeff72cae49529a8dba98ba01edc61ae367' 
  AND token = 'GL7kufVumh3Yj+e5uMKqNsrtjqYIuLVi54t8JFB7WX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}