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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ecb0b6014b2f956ccf468600a5c48ae5b38d34996953b0081d3cd458d32c498' 
  AND token = 'CGnTmjuOA+BOWWA/QYG0MdimapaH+i12WoCuHid+WTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}