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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd5fd3aeecdaa28f7499a64800f45cc9f2f5aa0f8c639bc17feec7d632a244e' 
  AND token = '/PWTPwOx900QSJGhtg1tkLi4QF0qOfJoZhhFAJjNIhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}