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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14726226cb1724bfe36e8f22eb6a146b747f78294f6b1bb5d46b8104e282c32' 
  AND token = 'NQnlYuF/UIbsqmWtDGGcjQK05R+cNc1S7zncYdGS5tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}