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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9970600972c5191e97c14757f0dee09126798823fb24cb512c5cbd8de1aa5fc4' 
  AND token = 'SiE6EXMT10wmL+jtv731KokxSvzY6mD+L/fOwuv6vMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}