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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04fcf569e5f3a5722f76220d546f79f9c80e5cf432835dd6434dec8d60b39521' 
  AND token = '1OqEGBEAXsNwHPXnxMREH1b1y2FDMSxLtEDtBrxDLcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}